Episode 39: The Science of GLP-1s: Food Noise, PCOS, Desire, and Why Your ADHD Brain May Respond Differently"
- Apr 7
- 2 min read

With Dr. Spencer Nadolsky
If you've ever been told you're just lazy, that you lack willpower, or that GLP-1s are some dangerous experimental drug — this episode is going to piss you off in the best way.
Dr. B sits down with obesity medicine specialist and lipidologist Dr. Spencer Nadolsky to cut through the noise and get into the actual science of GLP-1 medications — what they are, how they work in the ADHD brain specifically, and why ADHDers may be experiencing them differently than anyone's talking about.
They go deep on food noise (and why it's not just "being hungry"), the dopamine-reward connection, sexual desire changes, anhedonia, PCOS, binge eating, loose skin, and the very personal reality of what it's like to be an ADHDer on a GLP-1.
Oh, and Dr. B drops her own 84-pound journey — including the moment she cried in a parking lot over a pistachio cookie.
In this episode:
What GLP-1s actually are and where they came from (yes, including the lizard)
Food noise vs. hunger vs. cravings — they are not the same thing
Why the ADHD reward pathway means GLP-1s may hit differently for us
The real conversation about anhedonia, flatness, and sexual desire changes
PCOS, insulin resistance, and the ADHD overlap nobody's screening for
Binge eating disorder and ADHD — the research, the shame, and the relief




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